GLUCONEOGENESIS
|
Bottom Line: Glucose has to come from somewhere: that is where gluconeogenesis comes in. Gluconeogenesis is the pathway that allows the liver to make glucose from pyruvate. |
For a picture of gluconeogenesis, see Devlin, Figure 15.31
How is gluconeogenesis different?
 |
Click below the question to view the discussion. |
|
This content requires JavaScript enabled.
|
|
The liver's job is to make sure that levels of blood glucose are sufficiently maintained to support brain and RBC function. The actual levels of glucose can be regulated by the hormones insulin
and glucagon.
Reactions
|
Turn the pages by clicking on the right or left side of each page. |
|
This content requires JavaScript enabled.
|
|
Gluconeogenesis is almost like glycolysis run in reverse. However, there are three reactions in glycolysis that very strongly favor the glucose —> pyruvate direction. In gluconeogenesis these reactions are replaced by others that favor the pyruvate —> glucose direction.
