Stoichiometry of Fatty Acid Biosynthesis

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Biosynthesis of Longer-Chain Fatty Acids  

 The mitochondria and the endoplasmic reticulum are the sites where we make fatty acids longer than 16 carbons.  

 

Desaturation of Fatty Acids  

An enzyme complex in the endoplasmic reticulum inserts double bonds into fatty acids.   For example, in the case of stearoyl CoA, a cis-∆9 bond is inserted to form oleoyl CoA:

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