INTRODUCTION
Recall Objectives: Each first year medical student is expected to be able to:
- Know the various types of mutations: base substitution(transition, transversion), deletion and insertion
- Know the causes of mutation: Replication errors, environmental factors:
- Nitrous acid and alkylating agents, such as ethylene oxide
- UV and x-ray radiation
- Intercalating agents
- Crosslinking agents
Reference
Textbook of Biochemistry by Devlin, 7th edition, pp. 164-167