INTRODUCTION

Recall Objectives: Each first year medical student is expected to be able to:

1. Know the various types of mutations: base substitution(transition, transversion), deletion and insertion
2. Know the causes of mutation: Replication errors, environmental factors:

• Nitrous acid and alkylating agents, such as ethylene oxide
• UV and x-ray radiation
• Intercalating agents
• Crosslinking agents

Reference 

Textbook of Biochemistry by Devlin, 7^th edition, pp. 164-167

 

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