Gopu Changarathil, PhD
Department of Physiology
Gopu is a postdoctoral trainee in the lab of Lynette C Daws. There are no therapies currently available for substance abuse disorder - as in the case of stimulants abuse related to amphetamine. Hence, there is an urgent need to understand the addiction associated cellular/molecular changes in the brain which could contribute to developing efficient therapies. My research deals with identifying the function of OCT3 dopamine transporter of astrocytes in regulating amphetamine associated addiction behavior. As astrocytes make up the vast majority of the cells in the brain - my research aims to find direct links between astrocytes and substance abuse disorder.
CONTACT INFO:
RESEARCH AREAS
- Addiction
- Astrocytes
- Behavior
BIOGRAPHY
My name is Gopu. I received my PhD from University of Tsukuba, in 2019, under the supervision of Dr. Hiromi Yanagisawa. I am trained as a tissue stem cell biologist. After my graduation from Japan, I continued my research in UTSA where I looked at the function of neural stem cells in exacerbating acute/chronic epilepsy. When I am not in lab, I am a classical dancer – I am practicing usually or planning trips around US with my husband.
PUBLICATIONS
Raja E, Changarathil G, Oinam L, Tsunezumi J, Yen Xuan N, Ishii R, Sasaki T, Imanaka-Yoshida K, Yanagisawa H, Sada A (2022). The extracellular matrix fibulin 7 maintains epidermal stem cell heterogeneity during skin aging. Embo reports
Nieto-Estevez V, Changarathil G, Adeyeye AO, Coppin MO, Kassim RS, Zhu J, Hsieh J (2022). HDAC1 Regulates Neuronal Differentiation. Frontiers in Molecular Neuroscience
Oinam L, Changarathil G, Raja E, Ngo YX, Tateno H, Sada A, Yanagisawa H. (2020). Glycome profiling by lectin microarray reveals dynamic glycan alterations during epidermal stem cell aging. Aging Cell