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Tab Title: Point mutations

Tab Content:

Point mutations result from a single base substitution

a. Transitions - Substitution of a purine or pyrimidine by another purine or pyrimidine

b. Transversions - Substitution of purine by a pyrimidine or vice versa

Tab Title: Deletion and insertion mutations

Tab Content:

Deletion or insertion of one or more nucleotides in the DNA. If the mutation occurs in the coding region, the mutation may cause a shift in the reading frame of the genetic message (frame-shift mutations). A frame-shift mutation occurs when the insertion or deletion results in a change of the codon (three nucleotides) from the point of insertion or deletion.