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Lindsey Galbo-Thomma, PhD

Department of Pharmacology

Lindsey is a Postdoctoral Research Fellow in the laboratory of Dr. Charles P France. Her goals while training here are to gain expertise in the behavioral pharmacology of drugs using complex operant procedures and by examining other biobehavioral endpoints, such as ventilation and cognition, using highly translational nonhuman primate models. Another primary focus of her research will be to characterize putative pharmacotherapies for opioid use disorder.         

RESEARCH AREAS

  • Behavioral pharmacology
  • Self-administration
  • Preclinical models
  • Substance-use disorder
  • Cognition

BIOGRAPHY

Dr. Galbo-Thomma received her bachelor’s degree in biology from Allegheny College in Meadville, Pennsylvania where her undergraduate thesis focused on the withdrawal effects on the respiratory response in neonatal rats after chronic in utero exposure to morphine. Upon graduation she began working for Charles River Laboratories where she held positions as a Toxicology Research Biologist and a Toxicology Project Leader. She subsequently attended Northern Michigan University, earning a Master of Science degree in psychological science. Her thesis investigated norharmane and nicotine using a conditioned place preference assay in mice. Dr. Galbo-Thomma completed her PhD under the mentorship of Dr. Paul W. Czoty at Wake Forest University Graduate School of Arts and Sciences where she studied the effects of social stress/enrichment on ethanol self-administration and cognition in monkeys. While at Wake Forest she was awarded a F31 Predoctoral Research Fellowship Grant from the National Institute on Alcohol Abuse and Alcoholism. She designed experiments supporting the conclusion that the development of problematic drinking behaviors is partially driven by chronic, social stress, and that cholinergic agonists may be promising pharmacotherapies for treating the cognitive symptoms associated with heavy drinking. Lindsey is also involved in science and drug policy and outreach. She is currently a member on science policy and animals in research committees for several professional societies, including ASPET and CPDD, and was selected as the 2023-2024 AMP/ACNP BRAD Fellow.



PUBLICATIONS

Galbo-Thomma LK, & Epperly PM, Blough BE, Landavazo A, Saldaña SJ, Carroll FI, Czoty PW (2023). Cognitive-enhancing effects of acetylcholine receptor agonists in group-housed cynomolgus monkeys who drink ethanol. J Pharmacol Exp Ther, submitted

Galbo-Thomma LK, Davenport AT, Epperly PM, Czoty PW (2023). Influence of social rank on the development of long-term ethanol drinkng trajectories in cynomolgus monkeys. ACER. https://doi.org/10.1111/acer.15163

Galbo-Thomma LK and Czoty PW (2023). The use of touchscreen based methods to characterize effects of psychoactive drugs on executive function in nonhuman primates.. Current Pharmacology Reports, in press. https://doi.org/10.1007/s40495-023-00337-9

Stinson BT, Galbo-Thomma LK, Flynn SM, Gouin A, Epperly PM, Davenport AT, Czoty PW (2022)Punishment of ethanol choice in rhesus monkeys.. Behav Pharmacol. https://doi.org/10.1097/FBP.0000000000000683.

Hanlon CA, Smith HR, Epperly PM, Collier M, Galbo LK, Czoty PW (2022).Priming the pump? Evaluating the effect of multiple intermittent theta burst sessions on cortical excitability in a nonhuman primate model. Brain Stimulation. https://doi.org/10.1016/j.brs.2022.04.004

Galbo LK, Davenport AT, Daunais JB, Epperly PM, Stinson BT, Czoty PW (2022). Social dominance in monkeys: Lack of effect on ethanol self-administration during shedule induction. Alcohol. https://doi.org/10.1016/j.alcohol.2021.10.001

Tryhus AM, Epperly PM, Davenport AT, Galbo LK (2021). Effect of chronic binge-like ethanol consumption on subsequent cocaine reinforcement in rhesus monkeys. Drug and Alcohol Dependence https://doi.org/10.1016/j.drugalcdep.2021.108707

Hanlon CA, Czoty PW, Smith HR, Epperly PM, Galbo LK (2020). Cortical excitability in a nonhuman primate model of TMS. Brain Stimulation. https://doi.org/10.1016/j.brs.2020.10.008

Damuka, N, Czoty, PW, Davis, AT, Nader, MA, Nader, SH, Craft, S, Macauley, SL, Galbo LK , Epperly PE, Whitlow CT, Davenport AT, Martin TJ, Daunais JB, Mintz A, and Sai KKS (2020). Cortical excitability in a nonhuman primate model of TMS. Molecules. https://doi.org/10.3390/molecules25102289